Nafld score range. The NAFLD Fibrosis Score is a validated, noninvasive tool for identi...
Nafld score range. The NAFLD Fibrosis Score is a validated, noninvasive tool for identifying patients whose MASLD has advanced to liver fibrosis. Historically, the presence of NAFLD has been suspected in those presenting with abnormal liver blood tests or evidence of fatty changes on ultrasound. Completing the Calculator To complete the Non-Alcoholic Fatty Liver Disease (NAFLD) Fibrosis Score Calculator and score your patient: Any relevant data from the patient record automatically populates. For most people with NAFLD and a low FIB-4 score, annual monitoring is reasonable. 92). The management is with lifestyle measures, but it is important to identify those who are at risk of 4 days ago · Doctors used to call this condition NAFLD (non-alcoholic fatty liver disease) because tissues examined under a microscope resembled those of alcohol-associated liver disease, though the patients We would like to show you a description here but the site won’t allow us. The clinical utility of the FIB4 is thus in the general range reported for other published panels for NAFLD including the ELF score and Fibrotest which all require additional testing and add cost to the care provided to patients 11,14, 42. Siddiqui et al. 3 days ago · A FAST score is a noninvasive liver test that identifies people with a serious, progressive form of fatty liver disease. Find out about non-alcoholic fatty liver disease (NAFLD), a common condition where fat builds up in the liver. Feb 28, 2009 · Total NAS score represents the sum of scores for steatosis, lobular inflammation, and ballooning, and ranges from 0-8. Calculate NAFLD Fibrosis Score to assess liver fibrosis risk in non-alcoholic fatty liver disease. Fibrosis score F3: Severe liver scarring Fibrosis score F4: Advanced liver scarring (cirrhosis) Using your FibroScan fibrosis result to estimate your fibrosis score The table below shows liver diseases, ranges of fibrosis results, and the matching fibrosis score. Jul 27, 2025 · The NAFLD Fibrosis Score is calculated using six distinct variables, each offering insights into liver health and potential fibrosis progression. Jul 6, 2016 · Context Primary non-alcoholic fatty liver disease (NAFLD) is an excess of fat in the liver (steatosis) that is not a result of excessive alcohol consumption or other secondary causes. Nov 15, 2020 · Nonalcoholic fatty liver disease (NAFLD) is the most common form of liver disease in the United States, affecting up to 30% of adults. 3 days ago · Risk Stratification for NAFLD Adults with NAFLD or suspected NAFLD (obesity, type 2 diabetes, metabolic syndrome) require fibrosis risk stratification: 1 First-Line Fibrosis Assessment Use FIB-4 or NAFLD Fibrosis Score 1 For patients >65 years old, use FIB-4 threshold <2. We The NAFLD fibrosis score is used to distinguish between patients with nonalcoholic fatty liver disease who have (F3-F4) and do not have (F0-F2) advanced fibrosis. The Non-Alcoholic Fatty Liver Disease Fibrosis Score (NFS) is a widely used, non-invasive method that calculates the likelihood of advanced liver scarring, or fibrosis, in patients with NAFLD. It aims to improve how NAFLD is identified, diagnosed and managed with pharmacological and non-pharmacological treatment. Re-assess NAFLD risk score 3 years Fibroscans are performed by a trained Fibroscan technician who will provide the patient with the result, but is not trained to give clinical advice. It affects 20-30% of population (and the prevalence is increasing), and of these 5-6% can progress to NASH, fibrosis or cirrhosis. The ELF We would like to show you a description here but the site won’t allow us. Enter the required values to calculate the APRI value. The NAFLD fibrosis score calculator identifies liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). NAFLD Fibrosis Score Calculator Estimate the risk of liver fibrosis based on clinical and laboratory data The estimated range of the NAFLD fibrosis score is shown in Table 6. These secondary causes include side effects of certain medications, hepatitis C virus infection and particular endocrine conditions. Suspect a person has NAFLD if they have: Risk factors suggestive of the metabolic syndrome or other risk factors for NAFLD such as obesity, dyslipidaemia or hyperglycaemia. 3 were classified as not having advanced fibrosis, while patients with a FIB-4 score >2. NAFLD Fibrosis Score - The main calculator tab, complete as required. NAFLD Fibrosis Score Evidence - Displays further information about the calculator. Version 1 NAFLD risk assessment score (from table) The FIB-4 score and NAFLD fibrosis score are recom-mended for identifying patients at risk of fibrosis. If the FIB-4 score is in the indeterminate range, more frequent monitoring (every 6 months) and possible specialist referral are warranted. The severe form is called nonalcoholic steatohepatitis. Across the full range of the probability of stage 0-2 fibrosis (0% to 100%), the NAFLD fibrosis score is translated to a negative, positive, or indeterminate result. Tracking your CAP score over six to twelve months gives a clear picture of whether your liver fat is actually decreasing. The regression formula for prediction of severity of fibrosis is based on 6 variables: age (years), BMI (kg/m 2), IFG/diabetes, AST/ALT ratio, platelet Fibrosis-4 (FIB-4) Calculator Share The Fibrosis-4 score helps to estimate the amount of scarring in the liver. Calculate NAFLD (Non-Alcoholic Fatty Liver Disease) Fibrosis Score to assess liver fibrosis risk. Dec 17, 2023 · 2. The Fatty Liver Index diagnoses fatty liver using labs and exam findings. This tool does not provide medical advice, diagnosis, or treatment. Using your liver stiffness result to find your fibrosis score Your healthcare provider will use your liver stiffness result and medical history to find out your fibrosis score. NAFLD Fibrosis Score - The NAFLD fibrosis score is a simple noninvasive approach to identify patients that may have significant liver fibrosis and who therefore might benefit from additional studies such as elastography or liver biopsy. The NAFLD-LFS is a non-invasive screening method for liver fat in non-alcoholic fatty liver disease based on insulin, ALT and AST values and diagnosis of metabolic syndrome and type 2 diabetes. 88 (95% CI 0. A high FIB-4 score strongly suggests the presence of advanced liver fibrosis or cirrhosis. The spectrum ranges from simple steatosis characterized by the innocuous presence of fat droplets in hepatocytes, to the more advanced form of nonalcoholic steatohepatitis (NASH), and the more progressive and severe Your Fibroscan results explained Your "Liver Fat" score This is the Blue number on the scan – you will hear the medical community referring to it as the CAP score. Although several tools exist including the NAFLD Fibrosis Score (NFS) and the AST to Platelet Ratio Index, FIB-4 is the most well The AST to Platelet Ratio Index (APRI) determines the likelihood of hepatic fibrosis and cirrhosis in patients with Hepatitis C. The regression formula for prediction of severity of fibrosis is based on 6 variables: age (years), BMI (kg/m 2), IFG/diabetes, AST/ALT ratio, platelet The score should not be used as a surrogate for NASH diagnosis (see Brunt and Kleiner 2011 for details). Jun 13, 2020 · Histological Scoring System for Nonalcoholic Fatty Liver Disease Components of NAFLD Activity Score (NAS) and Fibrosis Staging Nonalcoholic Steatohepatitis Clinical Research Network Please mail comments, corrections or suggestions to the TPIS administration at the UPMC. 67 were classified as having advanced fibrosis. The nonalcoholic fatty liver disease fibrosis score (NFS) is comprised of unique metabolic risk indicators that may accurately predict residual cardiovascular (CV) risk in patients with established coronary disease and metabolic dysfunction. 85-0. This NAFLD fibrosis score calculator determines the degree of hepatic fibrosis in patients with non-alcoholic fatty liver disease. If too much fat stays in the liver, it can harm the organ and lead to serious health problems. It will appear in the oval on the far right (highlighted in yellow). Dec 16, 2024 · A FibroScan is a noninvasive test that uses ultrasound technology to measure liver stiffness, helping to assess liver health and detect fibrosis or fatty liver. A simple blood test can help identify those at risk. Jul 6, 2016 · This guideline covers how to identify the adults, young people and children with non-alcoholic fatty liver disease (NAFLD) who have advanced liver fibrosis and are most at risk of further complications. 0 (not <1. Please note: The use of the FIB-4 score is not validated where a patient is over 75 years of age. NAFLD ranges from hepatic steatosis, through inflammatory non-alcoholic NAFLD Fibrosis Score - The NAFLD fibrosis score is a simple noninvasive approach to identify patients that may have significant liver fibrosis and who therefore might benefit from additional studies such as elastography or liver biopsy. The guideline does A sample report can be seen below: In clinical trials for NAFLD/NASH diagnosis, patients with a FIB-4 score <1. Context Primary non-alcoholic fatty liver disease (NAFLD) is an excess of fat in the liver (steatosis) that is not a result of excessive alcohol consumption or other secondary causes. Populate the calculator with any Jan 1, 2024 · The NAFLD Familial Risk Score ranges from 0 to 6, and the projected risk of advanced fibrosis corresponding to this score is shown in Supplementary Table 4. In the reference study, NAS scores of 0-2 occurred in cases largely considered not diagnostic of NASH, scores of 3-4 were evenly divided among Jun 27, 2025 · A score in this range is inconclusive and signals the need for additional evaluation. The NAFLD fibrosis score has the benefit of a good negative predictive value for excluding Twenty percent of patients with NAFLD progress to nonalcoholic steatohepatitis (NASH), which is strongly linked to liver fibrosis and can lead to cirrhosis, liver transplantation, or death. Normal: This means your liver has no scarring, or mild scarring. This score helps medical professionals efficiently estimate the degree of potential liver We would like to show you a description here but the site won’t allow us. A score of 4 points or higher corresponds to a 13% or higher risk of NAFLD with advanced fibrosis. Mar 4, 2026 · Nonalcoholic Fatty Liver Disease is the build-up of extra fat in liver cells not caused by alcohol. It relies on readily available clinical information and routinely measured laboratory data. However for a certain number of these tests (BARD, FIB-4, NAFLD fibrosis score) much of the evidence is based on previously published and commonly agreed thresholds. Mar 10, 2026 · The NAFLD Fibrosis Score is a widely used, non-invasive tool that helps clinicians assess the risk of advanced liver scarring in patients with non-alcoholic fatty liver disease (NAFLD), now also termed metabolic dysfunction-associated steatotic liver disease (MASLD). Nov 17, 2022 · ELF score defines a three-marker fibrosis test (TIMP-1, PIIINP, HA) for assessing advanced fibrosis in NAFLD, guiding referrals and monitoring intervals. 7–10 ELF is included as a NAFLD Fibrosis Score NAFLD Fibrosis Score is a non-invasive tool used to assess the severity of fibrosis in patients with non-alcoholic fatty liver disease. Evaluate age, BMI, diabetes, AST/ALT ratio, albumin, and platelet count for accurate fibrosis prediction. AIM: To study whether the severity of liver fibrosis estimated by the nonalcoholic fatty liver disease (NAFLD) fibrosis score can predict all-cause mortality, cardiac complications, and/or liver complications of patients with NAFLD over long-term The nonalcoholic fatty liver disease fibrosis score (NFS) is comprised of unique metabolic risk indicators that may accurately predict residual cardiovascular (CV) risk in patients with established coronary disease and metabolic dysfunction. We would like to show you a description here but the site won’t allow us. 4 days ago · The fat measurement, called a CAP score, ranges from 100 to 400. Using your liver stiffness result to find your fibrosis score 3/8 Using your liver stiffness result to find your fibrosis score Your healthcare provider will use your liver stiffness result and medical history to find out your fibrosis score. Sep 28, 2023 · A comparison of brunt’s criteria, the non-alcoholic fatty liver disease activity score (NAS), and a proposed NAS scoring that includes fibrosis in non-alcoholic fatty liver disease staging. This colour coded chart from an organisation providing Fibroscans in the UK appears to contain similar CAP ranges to what is discussed in the NICE guidelines: We would like to show you a description here but the site won’t allow us. Share This is an A ST to P latelet R atio I ndex (APRI) calculator tool. 6 were indeterminate, requiring further testing. NAFLD ranges from hepatic steatosis, through inflammatory non-alcoholic Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of conditions associated with > 5% lipid deposition in the liver. Depending on score and local prevalence of advanced fibrosis, the score can be used to reliably predict (with high 80-low 90% accuracy) which patients are unlikely to have cellular evidence of fibrosis on biopsy. Clinical Significance Enhanced Liver Fibrosis (ELF) Score - The Enhanced Liver Fibrosis (ELF) score predicts progression to cirrhosis and liver-related events in patients with advanced fibrosis due to NASH. Clinical advice and decisions remains the responsibility of the referring Consultant. However, the full spectrum of NAFLD (from simple steatosis to steatohepatitis, cirrhosis and liver-related morbidity) can also be present with normal liver tests. NAFLD-FS is calculated using age, AST, ALT, platelet level, albumin level, presence of hyperglycemia, and Body Mass Index (BMI): all factors inversely related to severity of liver fibrosis in The NAFLD fibrosis score is used to distinguish between patients with nonalcoholic fatty liver disease who have (F3-F4) and do not have (F0-F2) advanced fibrosis. Persistent elevation of liver blood tests for 3 The combination of liver stiffness measurement and NAFLD fibrosis score improves the noninvasive diagnostic accuracy for severe liver fibrosis in patients with nonalcoholic fatty liver disease. Free online tool for medical professionals. The MELD Na Score (UNOS/OPTN) quantifies end-stage liver disease for transplant planning with addition of sodium. Age is a factor, as the prevalence of NAFLD and its progression to fibrosis tend to increase with advancing years. It recommends tools to assess the severity of NAFLD and gives advice on monitoring people with NAFLD for advanced liver fibrosis. Aug 4, 2025 · The NASH score is a valuable tool within the broader framework of managing non-alcoholic fatty liver disease (NAFLD) and NASH. It outlines the lifestyle changes and pharmacological treatments that can manage NAFLD and advanced liver fibrosis The Enhanced Liver Fibrosis (ELF) Score is a noninvasive test that indicates whether a patient with NASH and advanced fibrosis has a higher or lower risk of disease progression to cirrhosis (for those with F3 fibrosis) or other liver-related clinical events (for those with F3 or F4 fibrosis) within 1 to 4 years. Scores of 260 to 290 mean 34% to 66%, and anything above 290 means 67% or more. 7–10 ELF is included as a We would like to show you a description here but the site won’t allow us. Non-alcoholic fatty liver disease (NAFLD) affects approximately 30% of adults in developed countries. You can find the result interpretation and guidelines on the original study that published the score below the form. NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis, which may progress to liver fibrosis and cirrhosis with its complications. It stands for FibroScan-AST, and it combines three measurements to assess whether someone has fatty liver disease that’s actively causing inflammation and scarring. . Advanced liver fibrosis risk scores The National Institute for Health and Care Excellence (NICE) recommends considering the use of the Enhanced Liver Fibrosis (ELF) test to assess the risk of advanced liver fibrosis in people with suspected non-alcoholic fatty liver disease (NAFLD) [NICE, 2016]. The CAP score measures the levels of fat in the liver in decibels per meter (dB/m), this score ranges from 100-400 and can fluctuate over time. Your results can range from normal to advanced. 3) to improve accuracy 4 Second-Line Fibrosis Assessment Jun 9, 2020 · NAFLD is currently the most common liver disease in the United States, with a worldwide prevalence of 25% with imaging estimation (19). NAFLD affects 25% of the population, making it the most common liver disease worldwide. Enter the required values to calculate the FIB-4 value. A score of 238 to 260 indicates 11% to 33% of your liver is fatty. 3 days ago · Fatty liver disease is when too much fat builds up in the liver. The ELF score is not for use in the diagnosis of NASH, the staging of fibrosis, the serial monitoring of disease progression, or the monitoring of effects of therapeutic products. MASLD ranges in severity from hepatic steatosis — sometimes called diffuse hepatic steatosis, or formerly fatty liver infiltration or simply fatty liver — to a more severe form of disease called metabolic dysfunction-associated steatohepatitis (MASH), formerly called nonalcoholic steatohepatitis (NASH). Weight loss is the most effective treatment for NAFLD. Nov 25, 2023 · Read Also: What Salts Substitutes Can I Use For Fatty Liver Diet? Reversibility and Management of Fatty Liver Disease Based On Fibroscan Results Early Stages (Mild Steatosis): In the early stages, indicated by lower CAP scores, fatty liver is often reversible with lifestyle changes such as diet, exercise, and weight loss. The ranges of fibrosis results in the table are estimates. 4 days ago · What To Know About Fatty Liver Disease and Why It’s So Common News Article 3/19/2026 Adobe Stock WEDNESDAY, March 19, 2026 (HealthDay News) — Fatty liver disease is when too much fat builds up in the liver. , fibrosis-4 index or FIB-4) with a high negative predictive value (NPV) to exclude advanced fibrosis. The score ranges from 0 to 1, with higher numbers indicating a greater likelihood of significant liver City and Hackney Non-Alcoholic Fatty Liver Disease (NAFLD) pathway NAFLD comprises a spectrum of: fatty liver non-alcoholic steatohepatitis fibrosis cirrhosis. Jul 27, 2025 · What the NAFLD Fibrosis Score Is The NAFLD Fibrosis Score (NFS) is a non-invasive assessment tool designed to estimate the likelihood of advanced liver scarring (stages F3-F4) in individuals with Nonalcoholic Fatty Liver Disease. Note: NAFLD is now termed metabolic dysfunction-associated steatotic liver disease (MASLD), and nonalcoholic steatohepatitis (NASH) is called metabolic dysfunction-associated steatohepatitis (MASH). g. The NAFLD Fibrosis Score (NAFLD-FS) is the preferred non-invasive diagnostic option for detecting advanced fibrosis in NASH and is recommended by experts. The liver is the body’s filter. NAFLD-FS is calculated using age, AST, ALT, platelet level, albumin level, presence of hyperglycemia, and Body Mass Index (BMI): all factors inversely related to severity of liver fibrosis in The FIB-4 index is the preferred noninvasive initial test to assess the risk of NAFLD with liver fibrosis. Jan 12, 2025 · The Fatty Liver Fibrosis Score Calculator provides general health information for educational purposes only. Primary risk assessment of patients with fatty liver disease You should start with a serologic test (e. If left untreated, NAFLD can progress to advanced liver conditions, such as fibrosis, cirrhosis, and even liver cancer. It helps clean your blood, store energy and process nutrients that you eat. Jun 13, 2020 · Histological Scoring System for Nonalcoholic Fatty Liver Disease Components of NAFLD Activity Score (NAS) and Fibrosis Staging Nonalcoholic Steatohepatitis Clinical Research Network In most people, non-alcoholic fatty liver disease (NAFLD) is detected incidentally when liver blood tests or an abdominal ultrasound scan are performed for some other reason. ) Patients in the high-risk groups with an indeterminate or high FIB-4 index should be considered for further testing with the ELF score. (Repeat testing every 2 years is suggested for patients with a low FIB-4 index. The Enhanced Liver Fibrosis (ELF) Score is a noninvasive test that indicates whether a patient with NASH and advanced fibrosis has a higher or lower risk of disease progression to cirrhosis (for those with F3 fibrosis) or other liver-related clinical events (for those with F3 or F4 fibrosis) within 1 to 4 years. This NAFLD fibrosis score calculator stratifies the degree of fibrosis to the liver in nonalcoholic fatty liver disease patients by assigning a specific stage. Diagnosis of NASH (or, alternatively, fatty liver not diagnostic of NASH) should be made first, then NAS is used to grade activity. It provides specific information about the microscopic changes occurring in the liver. This guideline covers assessing and managing non-alcoholic fatty liver disease (NAFLD) in adults, young people and children. performed a cross-sectional study to determine the diagnostic utility of FIB-4 scores in a large, diverse population with NAFLD over time. 3-2. Nov 16, 2023 · Fibroscan CAP scores are discussed in detail on pages 62 to 74; the CAP scores summary is based on 5 studies. Your local guidance may differ. NAFLD can range from simple fatty liver (steatosis) to non-alcoholic steatohepatitis (NASH), which involves inflammation and liver damage. We Nov 28, 2025 · Non-Alcoholic Fatty Liver Disease (NAFLD) is the presence of excessive fat accumulation within liver cells. MASH causes the liver to swell or We would like to show you a description here but the site won’t allow us. [4] Those with FIB-4 scores 1. Using six routine clinical and laboratory parameters—including age, BMI, diabetes status, platelet count, albumin, and AST/ALT We would like to show you a description here but the site won’t allow us. There was again a very wide range of thresholds used that were often not pre-specified. FIB-4 Calculator for NAFLD NB: This is only valid for non-alcoholic fatty liver disease (NAFLD) and is intended for use in conjunction with the NCL Abnormal LFT pathway. Mar 28, 2025 · The nonalcoholic fatty liver disease (NAFLD) fibrosis score is a less invasive alternative to a liver biopsy that can help predict your risk for liver damage. Most experts recommend using 40 IU/L as the value for the AST upper limit of normal when calculating an APRI value. This scoring system had an area under the ROC curve of 0. The APRI Score will appear in the oval on the far right (highlighted in yellow). Jan 16, 2023 · The highest possible result is 75 kPa. Why is FIB-4 used in NAFLD? You may have heard that FIB-4 scores are most often used in the clinical setting of non-alcoholic steatohepatitis. wxw hoq wokudb peisr ptlpte sizx ewggek thyvoi tordsib gwdsu
